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Maternal witness defeat stress and THC exposure Pregnant dams received daily subcutaneous injections of THC (2 mg/kg, 2 ml/kg) or vehicle from gestational day 3 (GD3) until birth, corresponding to early-mid gestational periods of cortical and limbic development

In many cases, individuals may transition to a maintenance phase where injections are administered less frequently, such as once every two weeks or once a month

Novel therapeutic approaches involve mitochondrial-targeted antioxidants, combination anti-inflammatory and antioxidant strategies, ER stress modulators, and microbiote-targeted therapies

Human pregnancy serum contains at least two distinct proteolytic activities with the ability to degrade insulin-like growth factor binding protein-3

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