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During the acute phase, the METH-induced overactivation of the dopaminergic system causes euphoria, anxiety, and paranoid ideation (Moallem et al., 2018)

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(iii) thus, the rate of glycolysis (that would determine the rate of glucose consumption) could only be dictated by integration of allosteric signals on the only remaining regulated enzyme, the phosphofructokinase-1

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