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Moreover, MSC-Exos contain miRNAs that stimulate the Nrf2 antioxidant pathway [211], maintain the stability and function of SLC7A11 [166], and mitigate iron overload via DMT1 modulation [152]

PMID: 21 HaasCBEngelsEAHornerMJFreedmanNDLuoQGershmanSet al

About this article Cite this article Singh, V., Dziwornu, G.A

Since deletion of IL-1 reduces steatohepatitis, and fibrosis in mice fed a NASH-inducing diet (418), further investigation on the effects of canakinumab in human NASH are warranted

Psychiatric symptoms, anxiety and depression, were moderately correlated (r=0.55), but anxiety (HADSA) and motor severity (BFMDRS) showed weak correlations (r=0.25, p=0.08)