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Hypertension, another symptom of metabolic syndrome, showed variations in DNA modulations since it has been reported in hypertensive rat models a hypomethylation of the (pro)renin gene [142] or of the adrenergic 1 gene [143]

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Contribution of oxidative stress, apoptosis, endoplasmic reticulum stress and autophagy pathways to the ameliorative effects of hesperidin in NaF-induced testicular toxicity

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Shaw PJ (2005) Molecular and cellular pathways of neurodegeneration in motor neurone disease

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Model analysis Selection of parameters for estimation The methodology to select parameters for estimation involves first conducting local sensitivity analysis (LSA) to obtain a set of important parameters, and then determining from this set of parameters which are identifiable, that is for which parameters a value can be identified from the data, taking into account the model structure

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