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For example, an increased ratio of acylated to deacylated ghrelin can promote MASLD development by counteracting the compensatory inhibition of TNF--induced PANoptosis [183]

Lipid peroxidation is induced by hydroxyl, peroxyl, and alkoxy radicals that destroy the lipid membrane by interacting with the methylene group of fats

Targeting PANoptosis to regulate inflammatory cell death may exhibit therapeutic potential for treating inflammatory diseases and represents a promising target that requires further research to validate its feasibility

Cao S, Saw PE, Shen Q, Li R, Liu Y, Xu X

Liposomal products are typically more expensive and available as softgels or liquid formulations