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Mots-C is a mitochondrial-derived peptide associated with mitochondrial function, glucose homeostasis, and exercise-like metabolic responses

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10.2 Precision Oncology NNMT expression profiling may guide prognosis, predict therapy responsiveness, or support combination strategies with anti-angiogenic or epigenetic drugs in cancers such as OSCC, bladder cancer, pancreatic, or lung carcinoma

5 Implications and recommendations for future research As delineated in the text, NNMT is a crucial factor in MetS and has become a promising target for preventing or treating MetS-related diseases

3p and miR-378g, respectively, to upregulate the expression of NNMT, thereby inhibiting the osteogenic differentiation of BMSCs