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When compared to the control group, PZA treatment resulted in more than a 60% reduction in the viability of M

10.1016/j.molmed.2022.07.002 185

This surge in ROS overwhelms cellular antioxidant defenses, culminating in oxidative cell death

Cellular defenses are activated in response to insults to oxidized DNA and include four major repair mechanisms: 1 ) nucleotide excision repair (NER) and 2 ) base excision repair (BER), both of which excise bulky helix-distorting DNA lesions

While glutathione injections are generally considered safe, some individuals may experience mild side effects such as pain at the injection site, allergic reactions, or gastrointestinal issues