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Consequently, as its substrate, the lipid synthesis transcription factor SREBP1c, will correspondingly increase, thereby promoting the positive feedback loop of lipid generation, including PA, and advancing the progression of HCC [63]

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Toll-like receptor signaling pathways

134 However, because of heterogeneity among cancer cells, other studies have shown that IDH2 expression is decreased in metastatic HCC and gastric cancer tissues compared with paired normal tissues

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