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Description

A larger study is needed to elicit evidence that the HLA-B*58:01 allele can potentially be used as a genetic marker for allopurinol-induced SCARs among different ethnicities in Indonesia

A model of the chemoreflex control of breathing in humans: model parameters measurement

Anesthesiology 128 , 710717 (2018)

The first and rate-limiting step of the kynurenine pathway is catalyzed by the enzymes indoleamine-2,3-dioxygenase-1 (IDO-1) and tryptophan-2,3-dioxygenase (TDO) ( TDO2 , the gene encoding TDO, is mainly expressed in the liver, and IDO is known to be an important regulator of the immune system ( IDO1 and IDO2 in peripheral blood mononuclear cells was increased, which could be related to the elevated plasma IFN levels in these patients (Munn et al., 2005)