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10 this form of cell death was not inhibited by caspase inhibitors but could be suppressed by treating the cells with iron-chelating agents

Lipid peroxidation-dependent cell death regulated by GPx4 and ferroptosis

H.RodeckB.MannsM

Notably, excessive iron overload acts as a key driver of ferroptosis, a unique form of regulated cell death

Similar content being viewed by others Introduction Increased prevalence of obesity has led to a tsunami of metabolic diseases such as type 2 diabetes mellitus, dyslipidemia, and nonalcoholic fatty liver disease (NAFLD) 1