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This breakdown destabilizes the nanoparticles, leading to selective drug release inside the cells

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J Stem Cells 11(1):2536 Bloor AJC, Patel A, Griffin JE, Gilleece MH, Radia R, Yeung DT et al (2020) Production, safety and efficacy of iPSC-derived mesenchymal stromal cells in acute steroid-resistant graft versus host disease: a phase I, multicenter, open-label, dose-escalation study

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In conclusion, the future of ROS-based immunotherapy will not depend on globally altering systemic redox balance, but on the precise, spatially resolved reprogramming of cellular redox states