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Description

Phosphorylation of YAP results in cytoplasmic localization and degradation, while dephosphorylated YAP proteins translocate to nucleus and induce gene expression through interactions with TEA domain (TEAD) transcription factors

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Research Overview Nicotinamide N-methyltransferase (NNMT) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide, producing 1-methylnicotinamide and S-adenosyl-L-homocysteine [1]