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Growth Hormone Secretagogue Side Effects Since both hexarelin and ipamorelin increase growth hormone output, there is the possibility that they will induce accompanying side effects like [10]: Nausea Headache Joint pain Water retention Further, both ipamorelin and hexarelin are typically administered via subcutaneous injection

(4) This may lead to elevated levels of plasma growth hormone and insulin-like growth factor 1 (IGF-1)

Research also indicates that Ipamorelin may enhance the production of IGF-1 (Insulin-like Growth Factor 1) which is associated with processes involved in the growth and repair of muscular and skeletal tissues

IGF-1 LR3 works more subtly, optimizing natural processes rather than overriding them completely