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Importantly, we here demonstrate that the REW substitutions strongly attenuate binding to SpA (Fig S5r, s), and accordingly, IgG1-REW could efficiently engage C1q, even in the presence of 5-molar excess of SpA, which prevented binding to WT IgG1 (Fig

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Pregnancy can sometimes alter immune responses, making patch testing especially important

Multi-ancestry and multi-trait genome-wide association meta-analyses inform clinical risk prediction for systemic lupus erythematosus

Additionally, it can help to fade age spots, improve skin elasticity, and lessen the signs of sun damage