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Artesunate attenuates bone erosion in rheumatoid arthritis by suppressing reactive oxygen species via activating p62/Nrf2 signaling

3.4.3 BacA induce proliferation of CD8+, CD4+, and CD4CD45RO+ cells in calves at 16 weeks post-inoculation PBMCs from all treatment and control groups were analyzed by flow cytometry after stimulation with PPDa at 12-, 14- and 16-weeks post-inoculation, to evaluate the proliferation of CD4+, CD4+CD45RO+, CD8+, FOXP3+ and WC1+ T cell populations

It can be observed in transgenic mouse models (Srinivasan et al