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& Wei, Y

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For most patients on standard one- to three-month cycles, this situation should not arise if ordering is timed appropriately to protocol length

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Gastrointestinal effects usually settle across the first month, then return temporarily after each increase

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Different individuals would theoretically require different doses, and susceptibility to side effects would vary based on individual factors - data we simply don't have

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doi:10.1016/j.otc.2020.03.011

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