b12 injection with tirzepatide Lilly Says Compounded Added Vitamin Contains Impurities. Is It Safe? Tirzepatide with Methylcobalamin (B12) Injection

Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency

Most people start to feel the effects of increased energy and well-being within 24-48 hours of receiving the injection

B12 injections may be the better choice if you: Have severe, diagnosed B12 deficiency with neurological symptoms Have pernicious anemia requiring medical supervision Have had gastric bypass surgery affecting all absorption Prefer less frequent dosing and don't mind needles Have a medical condition requiring injectable B12 specifically Who Should Choose Oral Spray

Yes and the evidence is clear

the largest Phase 2b trial used 0.25, 0.5, and 1 mg/day for 24 weeks