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doi: 10.1002/jat.1275 75 GaoWChanJY-WWongT-S

[18] [21] In addition, it inhibits glutamine transporters and glutamate transporters, and thus blocks the reuptake of glutamine and glutamate

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Then, UPLC-grade water DDW:MetOH (3:1, v/v) solution (0.5 mL) containing internal standards: 13 C- and 15 N-labeled amino acids standard mix (Sigma-Aldrich) was added to the tubes, followed by centrifugation