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McGill University, Canada Carvalho AV, Canon E, Jouneau L, Archilla C, Laffont L, Moroldo M, Ruffini S, Corbin E, Mermillod P, Duranthon V (2017) Different co-culture systems have the same impact on bovine embryo transcriptome

MOTS-C MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a naturally occurring peptide encoded within mitochondrial DNA, playing a key role in cellular metabolism and energy regulation

FIGURE 1 Retinal eicosanoid pathways As dietary lipids supply the substrates for eicosanoid biosynthesis, observational data linking higher PUFA and lower saturated fat intake to less DR in well-controlled diabetes align with a model in which precursor pools influence pro- and anti-inflammatory lipid mediators ( COX pathway Cyclooxygenase-2 (COX-2) is upregulated in the diabetic retina, increasing conversion of arachidonic acid into bioactive prostanoids that regulate vascular permeability and inflammation