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A significant drop in serum ALT and AST indicated better liver integrity and less hepatic leakage

73, 74, 75, 76 Taken together, an acceptable hypothesis appears to be that increased claudin-2 expression in inflamed mucosa of IBD patients may help promote epithelial injury and repair

Furthermore, there is a positive correlation between serum IGF levels and testicular volume (95, 96), and administration of GH can significantly accelerate puberty if onset has been delayed (90, 97)