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Lancet Oncol (2011) 12:4955

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Glycines Role in Muscle Growth and Recovery As a major component of collagen, glycine is needed for maintaining muscle, tendon and joint health

Secondly, the existence of the blood-spinal cord barrier severely limits the permeability of many drugs (such as lamotrigine) at the injury site, resulting in the actual action concentration being lower than the theoretical effective threshold