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The adjustment from 4 to 3 severity groups did not impact the overall results

It also has dose-dependent immunoediting potential, influencing T-cell production and enhancing the function of effector T-cells while reducing regulatory T-cells (316)

doi: Toklu HZ, Hakan T, Celik H, Biber N, Erzik C, Ogunc AV, Akakin D, Cikler E, Cetinel S, Ersahin M, Sener (2010) Neuroprotective effects of alpha-lipoic acid in experimental spinal cord injury in rats