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This senescence-associated secretory phenotype is a result of the extrusion of cytoplasmic chromatin fragments in senescent cells, which act on the DNA sensing and effector cGAS-STING pathway to drive expression of interferon and NF-kB elements (Dou et al., 2017

At the tip of the arborising dendritic processes, the melanosomes are transferred to neighbouring keratinocytes [4, 6, 21, 22]

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A key characteristic of the cellular GSH pool is its high reduction state due to GR that is constitutively active and inducible upon oxidative stress (Figure 1: Regeneration)