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The protection provided by 4-ClDzp was similar to that observed after ischemia/reperfusion

doi: 10.1038/nature06009 54 LeungDYMartinRJSzeflerSJSherERYingSKayABet al

20,67 It is also suggested that TRF1-mediated intracellular iron uptake is required for ferroptosis, and using RNA interference with TRF1 can effectively prevent ferroptosis

An expansion of this study with a larger patient sample would help to understand if the different Grxs isoforms could characterize specific cancer cell subpopulations