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Indeed, despite the well-established procell survival function of SLC7A11 in the context of ferroptosis induction, other studies have uncovered an unexpected role of SLC7A11 in promoting cell death under glucose deprivation conditions (79, 8183)

Moreover, as a secondary analysis, the review relies entirely on published data and does not contribute original experimental findings, leaving it subject to the strengths and weaknesses of existing literature

Of the 42 peptides mentioned previously, 2 had precursor proteins that had a role in cell proliferation

Interestingly, in fibrils composed of mutant -syn, this buffering capacity was reduced (Ryan et al., 2018)