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Deficiency is rare in the developed world since meat is widely available and most grains and cereals are fortified with thiamine, but can occur in alcoholics and people who have undergone gastric bypass surgery

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In an experimental study, allogeneic islets were transplanted into the anterior chamber of the right eye of a diabetic recipient baboon, followed by an anti-CD154 antibody (an immunosuppressor) therapy (90)

By the remyelination phase, despite remaining separate from the controls, the microbial landscape appeared to shift closer to baseline, implying some degree of compositional recovery