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Histamine levels are positively correlated with estrogen, while progesterone and testosterone levels are negatively correlated in women and men respectively

IGF-1 naturally declines with age, and it is drastically reduced by oral estrogen in the oral birth control pill and by oral forms of estrogen used for menopausal HRT (transdermal estrogen does not have the first pass through the liver so does not decrease IGF-1)

Does conventional anti-bipolar and antidepressant drug therapy reduce NMDA-mediated neuronal excitation by downregulating astrocytic GluK2 function

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