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Additionally, because older individuals commonly take medications (polypharmacy), there is an increased possibility of interactions between drugs

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4.4.2 HER2, EPHA2 and IL13 receptor 2 as therapeutic targets of MB The systematic characterization of the tumor of the CNS identified HER2, HER3, NECTIN4, TROP2, CLDN6, CLDN18.2, and CD276/B7H3 proteins as potential therapeutic targets ( Figures 3 , 4 )

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The posterior longitudinal ligament, the anterior two-thirds of the dural sac (spinal meningeal layers), the anterior vascular plexus, and the latero-dorsal outer annulus of the intervertebral disk are all supplied by the sinuvertebral nerve during its course [11, 12]