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2277-C ALPHA-1 ANTITRYPSIN/PROTEINASE 3 IMBALANCE EXERTS PROTEOLYTIC REGULATION ON INTERLEUKIN-32 GAMMA TO PROMOTE NONALCOHOLIC STEATOHEPATITIS JeongSu Park 1 , Jin Lee 2 , Feng Wang 1 , Hwan Ma 1 , Yong-Sun Lee 3 , SangKyu Lee 4 , Yoon Mee Yang 5 , Hwan-Soo Yoo 1 , Sang-Bae Han 1 , Bumseok Kim 6 , Jin Tae Hong 1 and Yoon-Seok Roh 1 , (1)Chungbuk National University, (2)University of California, San Diego, (3)National Institute of Food and Drug Safety Evaluation, South Korea, (4)Kyungpook National University, (5)Kangwon National University, (6)Biosafety Research Institute and College of Veterinary Medicine, Jeonbuk National University, Iksan 54596, Korea

M.Urquidez-BejaranoP.de la Re-RodrguezC.Duarte-RodrguezL.SnchezF.et al

Neuroenergetics 5:11

In an AD mouse model, cognitive decline was associated with BMAL1/ARNTL deficiency, which promoted microglial-derived chronic inflammation through NF-B activation [384]

Photos: Courtesy of Brands Elizabeth Siegel is a freelance beauty writer who has covered skin care, plastic surgery, and more for Air Mail , Allure , Oprah Daily , W , Elle , and WWD