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Description

Proceedings of the National Academy of Sciences

Colonies were scraped from these plates and resuspended in 50 mL LB/Amp medium

For background on the GHRH pathway that CJC-1295 targets, Wikipedias growth hormone-releasing hormone overview provides foundational context

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Upon binding to IGF-1R, the peptide initiates multiple intracellular signaling cascades, including the phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway, which regulates protein synthesis and cell growth, and the mitogen-activated protein kinase (MAPK) pathway, which controls cell proliferation and survival