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MAOA up-regulation under androgen deprivation treatment induces mitophagy In addition to regulation of autophagy, increasing evidence has shown that ROS-induced mitochondrial depolarization initiates mitophagy, a selective type of autophagy in which dysfunctional mitochondria are removed by targeting to autophagic degradation 43

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Its development is caused by more pathogenic factors, among which intestinal flora dysbiosis is considered to be an important pathogenic mechanism of LMD

Several authors have proposed using a variety of agents to modulate the cellular damage associated with radiation exposure

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