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Hunt SA, Abraham WT, Chin MH, Feldman AM, Francis GS, Ganiats TG, et al

Glutathione conjugates to NAPQI, and the resulting ensemble is excreted

It has since gained transformative use in dermatology following the serendipitous discovery of its efficacy in infantile hemangiomas (IH), becoming the first FDA-approved systemic therapy for proliferating IH in 2014 given its vasoconstrictive and anti-angiogenic properties