These alumni, faculty, staff, and friends have made significant contributions to FACS Alumni initiatives, the college, the profession and/or society in general
Human pancreatic stellate cell (hPSC) culture and treatments HPSCs (Fenghui Biotechnology Co., Ltd., Changsha, China) were cultured in RPMI 1640 medium (Gibco) with glucose (5.5 mmol/L glucose) supplemented with 10% FBS (Gibco) in an incubator with 5% CO2 at 37 C
TB-500 single-compound vial for protocols that require TB-500 alone
Antioxidant defense system During oxidative stress and other stress conditions increased levels of H 2 O 2 is associated with elevated production of antioxidant enzymes 31
Curcumin increases intracellular ROS levels and a treatment with an antioxidant partially reverses the anti-proliferative effects of curcumin Since many curcumin-binding candidates identified in this study (CBR1/3, GSTP1/O1, NQO1/2, AKR1C1/D1, PRDX1, GLO1, and ADH1A shown in Table 1) belong to the enzymes involved in the metabolism of ROS and oxidative-stress products (such as Reactive Carbonyl Species, RCS) 18 , and because curcumin inhibits the enzymatic activity of CBR1 19 , GSTP1 20 , NQO1 21 , and GLO1 22 in vitro , we speculated that the treatment with curcumin up-regulates intracellular ROS levels in CML-derived leukemic cells
