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Cartilage degeneration was scored using the Yoshimi scale, which ranges from 0, defined as normal cartilage, to 5, defined as complete loss of cartilage

The mixture of compounds individually may be effective, however in combination they may exhibit more lipotropic activity than when administered alone in a synergistic fashion

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The physician will decide whether the missed dose needs to be given at a later time or if the regimen should be modified

But like most beneficial peptides, plasma concentrations decline sharply with age from roughly 200 ng/mL at age 20 to around 80 ng/mL by age 60