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This inhibition of angiogenesis is eliminated by co-administration with cytochrome P450 and COMT inhibitors, thereby confirming the involvement of cytochrome P450 enzymes in the blockade of tumor blood supply

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KEGG analysis identified fatty acid metabolism, biosynthesis of unsaturated fatty acids, steroid biosynthesis, retinol metabolism, and PPAR signaling pathway as those pathways most associated with differential RNA expression in recurrent NASH