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Imaging cerebrovascular effects Coexistent cerebrovascular disease is increasingly recognised as having a synergistic effect on synucleopathies 156 and multiple studies have assessed imaging markers of cerebrovascular disease in relation to outcomes in PD

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the prolonged exposure carries risks ranging from infection due to immune dysfunction in the days to weeks after an exposure to an increased risk of cancer to a longer-term effect such as atherosclerosis in later years

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