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doi: 10.1158/1078-0432.Ccr-13-2270 12 LaskoLMJakobCGEdaljiRPQiuWMontgomeryDDigiammarinoELet al

Thus, the protective effects of metformin on palmitate-induced cell death could result from partially inhibiting mitochondrial complex I, which would restore mitochondrial function and demonstrate the necessity of mitochondrial complex I in retarding or stopping the progression of NAFLD (32)