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In the treatment of IBD, therapeutic peptides are predominantly small molecules, typically comprising 210 amino acids, with 38 residues being most commona length that likely facilitates intestinal transport via peptide transporters while minimizing enzymatic degradation

The sheer number of s-nitrosylated proteins that deposit in Lewy Body aggregates suggests that RNS, once triggered, is accelerating not only aSyn aggregation but the aggregation of many proteins critical to neuronal survival and function

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