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Sequence alignment revealed that Fp GUS retains five of the six amino acids, termed the NFXAA motif where X is a hydrophobic residue, that make up the alpha helix conformation in the Rg GUS loop, indicating that Fp GUS may also be capable of forming this secondary structure motif even though this loop is disordered in the structure of this enzyme presented here

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It was found that dj-1 / zebrafish developed normally in the early stages, but showed lower levels of tyrosine hydroxylase, skeletal muscle respiratory failure, and lower body weight as development progressed (Edson et al., 2019)