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Its a compilation of 20 different surveys and involves nine thousand physicians, so the findings are highly significant

doi: 10.1016/j.tvjl.2007.04.005

1) may reflect, at least in some instances, potential target engagement by omaveloxolone leading to the transient increases in aminotransferases observed in MOXIe Part 2 [16, 20, 22,23,24]