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Recent human studies show that even short durations of moderate-intensity exercise (e.g., 15 minutes at ~55% heart rate reserve) can mobilize cytotoxic NK cells into the bloodstream ( dim and CD57 + NK cells, which have been observed to increase after moderate exercise in pediatric hematopoietic stem cell transplant recipients ( + ) remain elevated for more than an hour post-exercise, reinforcing the hypothesis that physical activity may contribute to immune-mediated senolysis ( These findings further support the concept that moderate-intensity exercise not only enhances immune surveillance of NK cells in the context of tumor defense but may also contribute to the clearance of senescent cells, thus playing a role in aging and tissue homeostasis

Epigenetic factors, such as DNA methylation, also modulate gene expression in hair aging

Diet and sperm quality: Nutrients, foods and dietary patterns

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A., Bucher J