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24 Secondly, activated Akt phosphorylates forkhead box O1 (FOXO1), a transcription factor upregulating gluconeogenesis rate-limiting enzyme such as phosphoenolpyruvate carboxykinase (PEPCK) and glucose-6-phosphatase (G6Pase), and translocate it from nucleus to cytoplasm, which inactivate its transcriptional activity, thus inhibiting gluconeogenesis

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49, 649 667.doi Meister A (1995) Glutathione biosynthesis and its inhibition

Fatigue, brain fog, and frequent illness can also point to oxidative stress

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