GSH1 Gamma glutamylcysteine synthetase, GSH2 Glutathione synthetase, GLR1 Glutathione oxidoreductase, GRX1-8 Glutaredoxins, GTO1-3 Glutathione transferases Omega-like, ROS Reactive oxygen species, RX Xenobiotics, GTT1-2 Glutathione transferases, GRX1-2 Glutaredoxins, YCF1 Vacuolar glutathione S-conjugate transporter, ECM38 Gamma-glutamyltranspeptidase, DUG1-3 GSH degradosomal complex -Glutamylcysteine synthetase (GSS1
FU and D-XZ revised the manuscript
CLEAN ENERGY & HEALTHY METABOLISM: Lipo B-complex is a dietary supplement that is designed especially for those dealing with low energy and wellness

Akt: Ak strain transforming AMPK: adenosine monophosphate-activated protein kinase EMT: epithelial to mesenchymal transition ERK: extracellular signal-regulated kinase GOT1: glutamic-oxaloacetic transaminase 1 GSH: glutathione H 2 O 2 : hydrogen peroxide HIF-1: hypoxia-inducible factor 1-alpha IL-2: interleukin-2 MAPK: mitogen-activated protein kinase MMP-9: matrix metallopeptidase 9 mTOR: mammalian target of rapamycin NADPH: nicotinamide adenine dinucleotide phosphate NF-B: nuclear factor kappa-light-chain-enhancer of activated B cells NOX4: nicotinamide adenine dinucleotide phosphate oxidase 4 Nrf2: nuclear respiratory factor 2 PD-1: programmed cell death protein 1 PD-L1: programmed death ligand 1 PI3K: phosphatidylinositol 3-kinase PTEN : phosphatase and tensin homolog deleted on chromosome 10 ROS: reactive oxygen species SOD2: superoxide dismutase 2 TGF-: transforming growth factor beta Tim-3: T cell immunoglobulin and mucin-domain-containing protein-3 TLRs: toll-like receptors VEGF: vascular endothelial growth factor Authors acknowledge Sumeet Singh (Guru Nanak Dev University, Amritsar) for assistance in drawing figures

Moreover, the increase in international air travel between countries with endemic dengue, often popular tourist destinations, and regions without the disease has heightened the risk of transmission [96]