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The treat-to-target ULT approach involves gradually increasing the dose of ULT to achieve the target serum urate concentration, which needs to be monitored periodically

Mutation can change the binding site of imatinib to the BCRABL (break point cluster regionAbelson murine leukaemia viral oncogene homolog 1) gene, thereby inhibiting the activity of imatinib amongst patients who have chronic myeloid leukaemia [87, 88]

Modification of P53 with O-Linked N-Acetylglucosamine Regulates P53 Activity and Stability

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

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