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Briefly, CO slices were treated with lipopolysaccharide (LPS) (Invivogen, San Diego, CA, USA, TLRL-3PELPS LPS) at 100 ng/mL for 3 h as a priming step

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A cross-sectional study of 280 SLE patients further indicated that higher adherence to a Mediterranean diet was significantly associated with lower disease activity, reduced cumulative organ damage, and decreased cardiovascular risk, suggesting that the Mediterranean diet may benefit SLE management and health improvement [103]

As shown in a mouse model of Fabry disease, intravenous administration of three AAV vectors carrying the -Galactosidase ( -Gal ) donor template and ZFN targeting the albumin locus resulted in robust supraphysiological -Gal activity in plasma and tissues