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[3] Concurrent use of oxidizing agents such as benzoyl peroxide can chemically degrade benzocaine, diminishing anesthetic efficacy

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However, the small minority of CBS deficiency patients carrying such mutations exhibit high plasma concentrations of total homocysteine and clinical symptoms indistinguishable from patients with variants in the catalytic domain

This finding suggests highly coordinated metabolic alterations within the pericardial fluid microenvironment, as previously reported 39

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