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AKT1 and AKT3 function similarly, and it has also been shown that overexpression of AKT1 induces myocardial hypertrophy, but loss of AKT1 leads to resistance to exercise-induced cardiac growth

Elevated 8-OHdG levels correlate with aging, cancer, diabetes, and neurodegenerative diseases, making it a critical tool for assessing oxidative DNA damage in clinical and experimental research ( Electron Paramagnetic Resonance Spectroscopy (EPR): It is a powerful tool to directly detect and quantify ROS in biological tissues

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Jana, A., Narula, P., Chugh, A

Interestingly, caveolin-1 overexpression protected and caveolin-1 knockout aggravated hepatic steatosis in HFD-fed mice by affecting lipogenesis, which indicates regulatory functions of caveolin-1 other than lipid transport in the liver [24]