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Phase 1 human trials have been registered in some geographies Published human efficacy data at the level of a completed, results-reported phase 2 study are not yet a settled part of the dataset Commercial development is active but has not produced a near-term approval path Patients and clinicians tracking 5-amino-1MQ should monitor ClinicalTrials.gov and peer-reviewed publications for current status

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[109] Four of the six coordination sites are provided by the corrin ring and a fifth by a dimethylbenzimidazole group

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12 Overall survival benefits have also been observed with the addition of isatuximab in a follow-up analysis of the ICARIA-MM study