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Moreover, BTZ influences the metabolism of the sphingomyelin synthesis pathway in the spinal dorsal horn by enhancing the expression of sphingosine-1-phosphate (S1P) and its receptor, S1PR1 (S1P receptor 1)

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In a systematic review of 16 observational studies that included 614, 392 individuals studied the effect of mRNA vaccines (Pfizer-BioNTech and Moderna) as well as adenoviral vector vaccines (Ad26.COV2.S and ChAdOx1) on long COVID post-vaccination were compared

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Alterations in these factors can lead to dysbiosisa state of microbial imbalance characterized by quantitative and qualitative changes in microbial populationsultimately contributing to impaired physiological function and disease susceptibility [16,19,20,21]