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Adequate selenium intake is mandatory for the normal function of thyrocytes, and selenium deficiency is associated with the decreased synthesis of thyroid hormones (191), increased thyroid volume, and increased number of thyroid nodules (182, 192)

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Thymosin alpha-1 supports T-cell maturation and dendritic cell function, making it relevant to studies of immunosenescence the age-related decline in immune competency documented across mammalian species including dogs

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